Biotechnology:
Gene Therapy (61)
See
also:
Sites:
- AG Vektorologie und Experimentelle Gentherapie
- Development of technologies
that exploit adenoviruses
as highly efficient vectors
for gene therapy. Includes
a range of publications
with abstract links.
- Alberta Gene Therapy Group - A network of researchers
looking to foster collaboration
in several therapeutic fields.
- Amaxa
Biosystems - NucleofectorTM
technology allows non-viral
gene transfer directly into
the nucleus of primary cells
and cell lines, thereby
providing rapid target gene
validation, acceleration
of drug development and
new applications for gene
therapy.
- American
Society of Gene Therapy
- Organization dedicated
to promoting gene therapy
research through public
education, scientific meetings
and scientific committees
targeting specific therapeutic
areas and also vector technology.
- Amsterdam
Molecular Therapeutics
- Focused on developing
gene therapies for lipoprotein
lipase disorder, inflammatory
bowel disease and neuroregeneration.
Also provides contract development
and manufacturing of gene
and cell-based products
in their GMP facility.
- Ark
Therapeutics - A gene
medicine company developing
a broad range of products
based on vascular and endothelial
molecular biology to treat
vascular and circulatory
diseases and cancer.
- BioVex
- Gene delivery technology
allowing pharmaceutical
and genomics companies to
assess the therapeutic value
of identified genes and
also allows genes to be
used as therapeutic products
to treat diseases from cancer
to nervous and immune system
disorders
- Cell Genesys - Focused on the development and
commercialization of cancer
vaccines and gene therapies
to treat various cancers
including leukemia, hemophilia
A and B, restenosis after
angioplasty and Parkinson's
disease.
- Center
for Cell and Gene Therapy
- Clinical and fundamental
research, job opportunities,
faculties' interests and
links to gene therapy sites
- joint project of Baylor
College of Medicine, Texas
Children's Hospital, and
The Methodist Hospital in
Houston, TX.
- Center
for Gene Therapy at the
University of Michigan Medical
Center - The center
links basic science, clinical
investigation and technology
transfer endeavors in the
area of gene therapy, while
also serving as a resource
for information and education.
- Centre
for Gene Therapeutics -
McMaster University
- The mission of the Centre
is to investigate, create
and implement approaches
utilizing the delivery of
genes as therapeutic agents
in the treatment of human
and animal disease.
- Ceregene,
Inc. - Pioneering genetic
therapies for neurologic
disorders.
- The Children's Hospital at Westmesd - Gene Therapy
Research Unit - A joint
initiative of The New Children's
Hospital and the Children's
Medical Research Institute
is undertaking gene therapy
clinical trials in Australia.
Research projects include
cancer immunotherapy, vector
development, HIV infection,
targeting gene delivery
to specific tissue types.
- Collateral Therapeutics - A product-driven cardiovascular
gene therapy company, focused
on the discovery, development
and commercialization of
novel and innovative non-surgical
gene therapy products.
- Copernicus Therapeutics, Inc. - Developing human
gene therapy products for
cystic fibrosis and hemophilia
B and DNA vaccinations.
The company creates proprietary
PLASmin Complexes which
are efficient non-viral
vectors and REPLIsome vectors
which allow replication
of non-viral vectors.
- Crucell
N.V. - Discover, develop
and produce a variety of
biopharmaceuticals for the
treatment of human diseases.
Includes technology and
investors data, and careeer
opportunities.
- Eleanor
Roosevelt Institute
- Conducts basic biomedical
research into therapies
for Down Syndrome, ALS,
cancer, and Rec8 Syndrome.
Includes map of chromosone
21, employment details and
links to related resources.
- enGene,
Inc. - Develop technology
to manufacture therapeutic
proteins through genetic
modification of gastrointestinal
cells to find a cure for
diabetes and its complications.
- European
Society for Gene Therapy
- ESGT - Organises annual
meetings in Europe to promote
gene therapy research.
- Finnish Gene Therapy Society - Fosters the exchange
of ideas between research
groups and individual scientists,
organizes scientific meetings
and training courses and
informs general public about
basic aspects and recent
developments in gene therapy.
- Gene
Express, Inc. - Provide
gene assays to assist pharmaceutical
and biotech companies with
new drug development and
multi-gene expression analysis
services to researchers.
Includes technology and
investor data, and careers.
- Gene Therapy - Human Genome Project - Definition,
hurdles, ethical issues,
and links to more resources
on gene therapy provided
by the Oak Ridge National
Laboratory.
- Gene Therapy Advisory Committee - GTAC - Advises
on the ethical acceptability
of proposals for gene therapy
research on humans taking
account of the scientific
merits and the potential
benefits and risks, and
provides advice to UK Health
Ministers on developments
in gene therapy research.
- Gene Therapy and Your Child - Development information
for the clinical use of
gene therapy for children
with severe illnesses.
- Gene Therapy at MD Anderson Cancer Center - The
human cancer gene prevention
and therapy program conducts
basic research, clinical
trials and vector development.
- Gene Therapy Systems - Commercial firm providing
reagents for gene delivery
and gene therapy research,
including unique pGeneGrip
fluorescently labeled plasmid
vectors and GenePORTER cationic
lipid transfection reagent.
- GeneBrowser
- Commercial site focusing
on the current state of
retroviral vector development
for gene therapy with numerous
helpful links - from Nature
Technology Corp.
- Genteric,
Inc. - A rapidly growing
biopharmaceutical company
that develops novel gene-based
methods to treat human diseases.
- GenVec
- An emerging biopharmaceutical
company developing novel
gene therapies for diseases
where local delivery of
a therapeutic gene has potential
benefits over currently
available treatments. New
product development initiatives
have been formalized for
coronary artery disease
with BioBypass angiogen,
restenosis prevention and
cancer.
- Goldyne Savad Institute of Gene Therapy - Aims
to enhance the development
of safe and effective gene
therapy by supporting research
projects, from vector development
and construction to production
of biologicals for human
use and their application
in GCP clinical trials.
- Harvard
Gene Therapy Initiative
- Provides plasmid construction
and virus production services
for gene therapy in both
research and therapeutic
applications.
- Henogen
- A GMP biomanufacturing
company located in Belgium,
able to produce, purify
and aseptically fill clinical
batches of therapeutic proteins,
monoclonal antibodies, plasmid
DNA, vaccinal viruses or
viral vectors for gene therapy.
- Inherinet - Consortium of researchers from European
institutions focused on
developing gene therapy
of hematopoietic stem cells
for inherited diseases.
- Introgen Therapeutics, Inc. - A leader in the
development of gene therapy
products to treat a variety
of cancers.
- InvivoGen - Tools for gene therapy and cancer
research including plasmid
and cloning vectors, gene
collections, selection antibiotics,
mycoplasma curing kit, and
prodrugs.
- Jesse's
Journey - The Foundation
for Gene and Cell Therapy
- A registered charitable
organization raising funds
for research in gene and
cell based therapies focusing
on Duchenne muscular dystrophy
and other neuromuscular
diseases.
- The Journal of Gene Medicine - An information
source on all aspects of
human gene therapy. It offers
an international comprehensive
summary of both published
and ongoing clinical trials.
Also includes reviews on
basic and therapeutic issues.
- Molecular
Medicine Bioservices, Inc.
- A development and manufacturing
company based in San Diego
dedicated to the production
of high-quality, clinical
grade, gene and cell based
therapeutics and reagents.
- Molecular Virology Lab at Leiden University -
The group performs basic
research on viruses in order
to facilitate the development
of efficient gene-transfer
vectors for use in gene
therapy. Current research
concerns the human adenoviruses
and the systems required
for producing recombinant-adenovirus
vectors.
- MolecularTrucks, Inc - Sells AAV purification
kits of different serotypes
for gene therapy research.
Includes online buying facilities.
- National
Gene Vector Laboratories
(NGVL) - An interactive
group of academic production
and pharmacology/toxicology
laboratories whose primary
goal is to provide eligible
investigators with clinical
grade vectors for phase
I/II gene therapy clinical
trials and to provide support
for relevant pharmacology/toxicology
studies leading up to clinical
gene transfer protocols.
- Office
of Biotechnology Activities
at the NIH - Monitors
scientific progress and
ethical issues in basic
and clinical research involving
recombinant DNA and human
gene transfer at NIH funded
institutions.
- Oxagen
Limited - Perform genetic
analysis on collections
of family samples so as
to understand the mechanisms
and causes of common diseases,
in order to identify new
drug targets, the validation
of targets and the development
of diagnostics.
- Oxford Biomedica - Focuses on developing gene
transfer technologies for
human gene therapy, gene-based
immunotherapy, and gene-based
drug discovery for cancer,
AIDS, neurodegenerative
and cardiovascular disease.
- Oxford University GeneMedicine Research Group
- Focused on the development
gene therapies for diseases
of the airway, such as asthma,
lung cancer and in particular,
cystic fibrosis (CF). Work
includes formulation development,
reagent production, pre-clinical
testing, and human clinical
trials.
- Pittsburgh Human Gene Therapy Center - Fosters
the growth and development
of multidisciplinary preclinical
and clinical research programs
aimed at the use of gene
transfer technologies for
the treatment of human disease.
- Polyplus Transfection - Dedicated to the development,
manufacturing and marketing
of modular transfection
reagents. Expertise includes
in vitro and in vivo gene,
oligonucleotide and siRNA
delivery, transient and
stable cell transfection,
automation and protein production
in animal cells.
- Puresyn,
Inc. - Develops separation
and purification processes
for manufacturing gene delivery
products such as supercoiled
plasmids, synthetic oligonucleotides,
recombinant adenovirus and
adeno-associated virus.
- Qugen
Therapeutics Pte Ltd
- Focuses on the development
of novel gene-based technologies
and products providing first
proof of principle data
in pre-clinical models and
then moving these technologies
into the clinical setting.
- Replicor,
Inc. - Development of
technologies controlling
DNA replication for applications
in a platform for gene therapy
vectors and in the discovery
of new therapeutic agents
for cancer and tissue regeneration.
- Retroscreen Ltd. - Virological research and clinical
trials company that work
on most model systems and
carry out projects from
laboratory based assays
to full ethics committee
approved clinical trials.
- Salus
Therapeutics, Inc. -
Developed a series of proprietary
technologies for the discovery,
development and delivery
of nucleic acid-based therapeutics,
including antisense and
gene therapy drugs.
- Selective Genetics - Aims to commercialize site-specific
gene therapeutics and DNA
devices for tissue repair
and regeneration.
- Targeted Genetics Corporation - Develops gene
delivery technologies and
therapeutic products based
on gene delivery.
- Transgene
S.A. - Gene therapy
company based in France
is developing products for
cancer and cystic fibrosis.
Vector platforms include
adenovirus, retrovirus,
vaccinia virus, cellular
and synthetic vectors.
- UCSD Program in Human Gene Therapy - Facilitates
the application of basic
and pre-clinical research
to the treatment of human
disease through vector development
and gene discovery and characterization.
- University of Minnesota Gene Therapy Center -
Clinical gene therapy research
programs focusing on metabolic
disorders.
- University of North Carolina Chapel Hill Gene Therapy
- Working to translate gene
therapy research from the
laboratory bench into Phase
I clinical trials for the
treatment of hematologic
and endocrine diseases.
The center has a GMP facility
for clinical grade gene
vector production.
- Valentis,
Inc. - Developing gene-based
therapeutics or "gene medicines"
for the treatment of certain
cancers, neuromuscular,
cardiovascular, rheumatological
and pulmonary diseases.
- Virapur
- Sells virus purification
kits for gene therapy and
virus research which do
not require cesium gradients.
- VirRx,
Inc. - A biotechnology
company with a primary interest
in cancer gene therapy.
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