Northfield Labs About
Northfield Lavs Northfield Laboratories Inc. is a leader
in developing an oxygen-carrying blood
substitute for the treatment of urgent,
large volume blood loss in trauma and
resultant surgical settings. Northfield’s
product, PolyHeme®, is unique among hemoglobin-based
oxygen-carrying blood substitutes in development.
PolyHeme® simultaneously restores lost
blood volume and hemoglobin levels and
is designed for rapid, massive infusion.
PolyHeme® requires no cross-matching.
It is compatible with all blood types
and therefore immediately available for
infusion. It has an extended shelf life
of over 12 months. PolyHeme® is a unique human hemoglobin-based
oxygen-carrying blood substitute in development
for the treatment of urgent, large volume
blood loss in trauma and surgical settings,
with a particular focus on settings where
blood is not immediately available. PolyHeme®
is a solution of chemically modified human
hemoglobin which simultaneously restores
lost blood volume and hemoglobin levels
and can be rapidly and massively infused.
PolyHeme® has been rapidly and safely
infused in clinical trials in sufficiently
massive quantities to be useful in the
treatment of large volume blood loss.
Clinical
Trials for Northfield NX 473 is a next-generation platinum
compound for cancer treatment. It has
been tested extensively in preclinical
studies, and has been evaluated in more
than 500 patients in Phase I and II clinical
trials. NX 473 has demonstrated activity
as a single agent in patients with lung
cancer, ovarian cancer, and hormone refractory
prostate cancer, More
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